CHARACTERISTICS OF CHARLSON COMORBIDITY INDEX AND RELATED FACTORS IN PATIENTS ON MAINTENANCE HEMODIALYSIS
Main Article Content
Abstract
Objectives: To evaluate the characteristics of the Charlson comorbidity index (CCI) and identify associated factors in patients undergoing maintenance hemodialysis (MHD). Methods: A cross-sectional descriptive and analysed study was conducted on 114 MHD patients at Military Hospital 103 from June 2025 to May 2026. Data were collected from medical records and direct patient interviews. Collect clinical and paraclinical data and assess CCI using the Vietnamese-adapted Charlson scale. Results: The mean age of the patients was 58.99 ± 14.07 years, with males accounting for 52.6%. The mean duration of dialysis was 67.38 ± 55.99 months. The mean CCI score was 3.74 ± 1.52; the majority of patients had a CCI ≤ 4 (72.8%), while only 4.4% had a CCI ≥ 7, indicating a mild-to-moderate comorbidity burden. The most common comorbidities were heart failure, chronic liver disease, and diabetes mellitus. The CCI score increased with age and showed significant associations with serum albumin and hemoglobin levels, suggesting that comorbidity burden may reflect nutritional status. Conclusion: Most MHD patients had a mild-to-moderate comorbidity burden. The CCI score increased with age and was strongly associated with nutritional indicators, particularly albumin and hemoglobin. The CCI is a supportive tool for risk assessment and stratification in MHD patients.
Keywords
Charlson's comorbidity index, Chronic kidney disease, Hemodialysis
Article Details
References
2. Liu Y, Yang C, et al. Association between the Charlson comorbidity index and the risk of 30-day unplanned readmission in patients receiving maintenance dialysis. BMC Nephrology. 2019; 20:363.
3. https://freseniusmedicalcare.com/ content/dam/fresenius-medical-care/ global/en/04_media/pdf/FME_Annual_Report_2022_EN.pdf. Fresenius Medical Care Report. 2022.
4. Yu Y, Li F, et al. Comorbidity indices and mortality in maintenance hemodialysis. Ageing Med. 2024; 7(6):737-743.
5. Lalo R, Kamberi F, et al. Burden of hemodialysis on health‑related quality of life: Insights from a multi‑center cross‑sectional analysis in Southern Albania. Front Med. 2025; 12:1557063.
6. KDIGO. Clinical Practice Guideline for CKD. Nutrition & Anemia Update. 2024 - 2026.
7. Elhassan S, Abdelhadi I, et al. Malnutrition among patients with end‑stage renal disease in war 2024: The role of healthcare access, dialysis, gender, and economic disparities. International Journal for Equity in Health. 2025; 24:298.
8. Flores-Mendoza A, Garcia-Campa M, et al. Charlson comorbidity index and mortality in hemodialysis. BMC Nephrol. 2025; 26(1):376.