ĐÁNH GIÁ BƯỚC ĐẦU KẾT QUẢ VÀ TÍNH AN TOÀN CỦA TRUYỀN LIDOCAIN 0,5% LIÊN TỤC TẠI VẾT MỔ BẰNG CATHETER TRONG GIẢM ĐAU SAU MỔ GHÉP GAN

Abstract

Objectives: To evaluate the analgesic efficacy and safety of continuous wound catheter infusion with 0.5% lidocaine combined with multimodal analgesia for postoperative pain control in liver transplant recipients. Methods: A prospective, descriptive study was conducted on 10 patients undergoing liver transplantation at Military Hospital 103 from January 2025 to December 2025. All patients received continuous infusion of 0.5% lidocaine via a multi-orifice wound catheter at a rate of 4 - 6 mL/hour combined with postoperative paracetamol and nefopam. Pain intensity (VAS at rest and during movement), fentanyl rescue requirements, patient satisfaction, and adverse events were recorded at 6, 12, 24, and 48 hours postoperatively. Results: Mean VAS scores at rest were 1.3 ± 0.8 and 0.8 ± 0.5 at 6 and 48 hours, respectively. VAS during movement was 3.2 ± 0.9 and 2.2 ± 0.6, respectively. Only 20.0% of the patients (2/10) required fentanyl rescue. One case (10.0%) experienced mild nausea, which resolved spontaneously within 12 hours. Patient satisfaction rate was 90.0%. Conclusion: Continuous wound catheter infusion with 0.5% lidocaine combined with multimodal analgesia provides effective and safe postoperative pain management in liver transplant patients.