EVALUATION OF THE EFFECTIVENESS OF AUTOLOGOUS BLOOD PATCHING IN REDUCING COMPLICATIONS OF COMPUTED TOMOGRAPHY-GUIDED PERCUTANEOUS LUNG BIOPSY

Duc Huy Nguyen1, Ngoc Bang Dao1, Ba Thang Ta1, Thi Kim Nhung Pham1, Quoc Tuan Bach1, Hoang Cuong Nguyen1,
1 Military Hospital 103

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Abstract

Objectives: To evaluate the effectiveness of autologous blood patching in reducing complications of computed tomography (CT)-guided percutaneous lung biopsy. Methods: A prospective, cross-sectional descriptive study with longitudinal follow-up was conducted on 79 patients who underwent CT-guided percutaneous lung biopsy at Military Hospital 103 between September 2024 and January 2026. Among them, 36 patients underwent lung biopsy with autologous blood patching (group 1), while 43 patients underwent lung biopsy without autologous blood patching (group 2). Results: The study population consisted predominantly of elderly patients, with males accounting for 68.35% of the cohort. Chest CT demonstrated that lesions were most frequently located in the right upper lobe, with the majority measuring < 3cm in diameter. Irregular lesion margins were the most common radiological feature. The median number of biopsy specimens obtained was three. Adenocarcinoma was the most common malignant histopathological diagnosis, whereas tuberculous inflammation was the most frequently identified benign lesion. The incidence of pneumothorax was higher in group 2 than in group 1 (51.16% vs. 33.33%), although the difference was not statistically significant (p > 0.05). Progressive pneumothorax within 24 hours after the procedure was observed only in group 2 (18.6%). Conclusion: CT-guided percutaneous lung biopsy with autologous blood patching is a safe technique, provides a high diagnostic yield, and may reduce the incidence of post-biopsy pneumothorax.

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References

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