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Issue: Vol. 51 No. 6 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.6 - 2026
Section: Articles
DOI: 10.56535/jmpm.v51i6.1882
Date Published: 28/06/2026
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Trinh, T. S., Nguyen, T. D., Trinh, A. T., Pham, D. M., Pham, V. Q., & Trinh, Q. T. (2026). AGE-RELATED CHANGES IN REPRODUCTIVE HORMONE CONCENTRATIONS AMONG INFERTILE MEN. Journal of Military Pharmaco-medicine, 51(6), 88-97. https://doi.org/10.56535/jmpm.v51i6.1882

AGE-RELATED CHANGES IN REPRODUCTIVE HORMONE CONCENTRATIONS AMONG INFERTILE MEN

The Son Trinh1, , Thuy Duong Nguyen2, An Thien Trinh1, , Duc Minh Pham1, Van Quyet Pham1, Quoc Thanh Trinh1
1 Military Institute of Clinical Embryology and Histology, Vietnam Military Medical University
2 Vietnam Academy of Science and Technology

Main Article Content

Abstract

Objective: To evaluate age-related changes in reproductive hormone concentrations among men seeking infertility evaluation. Methods: A cross-sectional descriptive study was conducted among 410 men of reproductive age, stratified into 3 groups: 200 men with normozoospermia, 170 with severe oligozoospermia, and 40 with azoospermia. Results: In the normozoospermic group, there was a weak positive correlation between age and FSH (follicle-stimulating hormone)concentrations (r = 0.2689; p =0.0001) and a very weak positive correlation between age and LH (luteinizing hormone) concentrations (r =0.1594; p =0.0242). A statistically significant age-related increase in FSH and LH concentrations was also observed in the severe oligozoospermia group; however, this trend was not significant in the azoospermia group. Testosterone concentrations showed no statistically significant relationship with age across all three groups. Conclusion: In the normozoospermia and severe oligozoospermia groups, FSH and LH concentrations tended to increase with age, whereas age-related changes were not significant in the azoospermia group. Testosterone concentrations remained unchanged with age in all three groups.

Keywords

FSH, LH, Testosterone, Age-related, Andropause

Article Details

References

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