Article Sidebar

PDF
Date Published: 28/01/2026
Abstract Views: 88
Views PDF: 44
DOI: 10.56535/jmpm.v51i1.1736
Issue
Vol. 51 No. 1 (2026): JOURNAL OF MILITARY PHARMACO-MEDICINE No.1 - 2026
Section
Articles
How to Cite
Nguyen, H. T., Pham, K. H., Ha, V. T., & Vu, H. B. (2026). CHARACTERISTICS OF NUTRITIONAL STATUS IN GASTRIC CANCER PATIENTS FOLLOWING SURGICAL TREATMENT AND CHEMOTHERAPY AT MILITARY HOSPITAL 103. Journal of Military Pharmaco-medicine, 51(1), 77-83. https://doi.org/10.56535/jmpm.v51i1.1736

CHARACTERISTICS OF NUTRITIONAL STATUS IN GASTRIC CANCER PATIENTS FOLLOWING SURGICAL TREATMENT AND CHEMOTHERAPY AT MILITARY HOSPITAL 103

Nguyen Huu Thien1, , Pham Khanh Hung1, Ha Van Tri1, Vu Huy Bon1
1 Khoa Hóa trị, Trung tâm Ung bướu, Bệnh viện Quân y 103, Học viện Quân y

Main Article Content

Abstract

Objectives: To describe the characteristics of nutritional status in gastric cancer patients following surgery and chemotherapy at Military Hospital 103. Methods: A retrospective, cross-sectional descriptive study was conducted on 60 gastric cancer patients who underwent surgery and received 6 cycles of adjuvant chemotherapy with the FOLFOX regimen (3/2024 - 3/2025). Results: The rate of malnutrition before chemotherapy was 30%; the prevalence of malnutrition after chemotherapy was higher than before chemotherapy (p < 0.001). Logistic regression analysis revealed risk factors for malnutrition after chemotherapy, including age ≥ 60 years (OR = 9.0), self-provided diet (OR = 21.0), advanced stage III - IV disease (OR = 5.7), non-intestinal histology (OR = 6.6), and baseline PNI < 45 (OR = 25.6). Conclusion: The prevalence of malnutrition among gastric cancer patients after surgery and chemotherapy ranged from 30.00 - 36.67%. Major risk factors include older age, self-provided diet, advanced disease stage, non-intestinal histology, and low PNI. 

Keywords

Gastric cancer, Chemotherapy, Malnutrition, PNI, BMI

Article Details

References

1. Sung H, Ferlay J, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. J CA: A Cancer Journal for Clinicians. 2021; 71(3):209-249.
2. Arends J, Baracos V, et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017; 36(1):11-48.
3. Ryu SW KI, Comparison of different nutritional assessments in detecting malnutrition among gastric cancer patients. World J Gastroenterol. 2010; 16(26):3310.
4. Pressoir M, Berchery D, et al. Prevalence, risk factors, and clinical implications of malnutrition in French Comprehensive Cancer Centres. Br J Cancer. 2010; 102(6):966-971.
5. Zhang X, Zhang J, et al. Prognostic Nutritional Index (PNI) as a predictor in patients with metabolic syndrome and heart failure. Diabetes Metab Syndr Obes. 2023; 16:2503-2514.
6. Cederholm T, Jensen G, et al. GLIM criteria for the diagnosis of malnutrition - a consensus report from the global clinical nutrition community. Journal of Cachexia, Sarcopenia. 2019; 10(1):207-217.
7. Guo Z, Li W, et al. Changes in nutritional status and body composition in gastric cancer after surgery and adjuvant chemotherapy. Asia Pac J Clin Nutr. 2016; 25(2):273-280.
8. Mohri Y, Tanaka K, et al. Prognostic nutritional index predicts postoperative outcome in colorectal cancer. Ann Surg Oncol. 2013; 20(3):3963-3970.
9. Lauren P. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. Acta Pathol Microbiol Scand. 64:31-49.
10. Nguyễn Thị Thúy, Lê Thị Hương, Nguyễn Thị Thanh, Đánh giá tình trạng dinh dưỡng ở bệnh nhân ung thư dạ dày sau hóa trị tại Bệnh viện K. Tạp chí Y học Việt Nam. 2022; 515(1):52.