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Date Published: 28/12/2025
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DOI: 10.56535/jmpm.v50i9.1704
Issue
Vol. 50 No. 9 (2025): JOURNAL OF MILITARY PHARMACO-MEDICINE No.9 - 2025
Section
Articles
How to Cite
Do, T. D., Phan, T. H. T., & Nguyen, K. O. (2025). PREGNANCY OUTCOMES OF WOMEN WITH MONOCHORIONIC DIAMNIOTIC TWIN PREGNANCIES COMPLICATED BY TWIN REVERSED ARTERIAL PERFUSION SEQUENCE TREATED IN HA NOI OBSTETRICS AND GYNECOLOGY HOSPITAL. Journal of Military Pharmaco-medicine, 50(9), 172-179. https://doi.org/10.56535/jmpm.v50i9.1704

PREGNANCY OUTCOMES OF WOMEN WITH MONOCHORIONIC DIAMNIOTIC TWIN PREGNANCIES COMPLICATED BY TWIN REVERSED ARTERIAL PERFUSION SEQUENCE TREATED IN HA NOI OBSTETRICS AND GYNECOLOGY HOSPITAL

Tuan Dat Do1,2, , Phan Thị Huyền Thương1,3, Nguyễn Kiều Oanh3
1 Bệnh viện Phụ sản Hà Nội
2 Trường Đại học Y Hà Nội
3 Trường Đại học Y Dược, Đại học Quốc gia Hà Nội

Main Article Content

Abstract

Objective: To evaluate of pregnancy outcomes in women with monochorionic diamniotic twin pregnancies complicated by twin reversed arterial perfusion (TRAP) sequence treated in Ha Noi Obstetrics and Gynecology Hospital.

Methods: An interventional prospective study was conducted on 15 pregnant women diagnosed with twin reversed arterial perfusion (TRAP) sequence who treated fetal intervention and delivered at Hanoi Obstetrics and Gynecology Hospital, with neonatal follow-up for at least 6 months after birth in 2020 - 2021.

Results: Fetoscopic laser photocoagulation was successfully performed in all cases of acardiac twin (100%), most commonly at 19 weeks of gestation. Neonatal survival after intervention was 73.32%, with 8 out of 11 neonates delivered at term. The mean prolongation of pregnancy was 10.73 weeks. The average gestational age at delivery was 36 weeks. The most frequent Apgar scores at 1 and 5 minutes were 7 and 8, respectively. The majority of neonates weighed >2500 g (63.64%). All infants had a normal Karyotype, and no neurodevelopmental abnormalities were detected by Denver II assessment at 6-month follow-up.

Conclusion: Fetoscopic laser surgery for acardiac twin was associated with a high neonatal survival rate (73.32%) and prolonged pregnancy by an average of 10.7 weeks. Most neonates demonstrated favorable perinatal outcomes, and all infants showed normal findings on postnatal follow-up.

Keywords

Monochorionic diamniotic twin pregnancies affected by TRAP sequence, Obstetric outcomes after treatment of TRAP sequence, Neonatal outcomes after treatment of TRAP sequence, Twin reversed arterial perfusion

Article Details

References

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