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Date Published: 10/12/2025
Abstract Views: 13
Views PDF: 5
DOI: 10.56535/jmpm.v50si4.1624
Issue
Vol. 50 No. si4 (2025): JOURNAL OF MILITARY PHARMACO-MEDICINE - SPECIAL ISSUE 12/2025
Section
Special issue celebrating the 75th anniversary of Military Hospital 103
How to Cite
Pham, V. C., Ngo, Q. L., Nguyen, Q. H., Dang, V. B., Nguyen, V. T., Vu, D. D., Le, H. N., Phung, T. P. T., & Vu, M. D. (2025). ASSESSMENT OF THE VALUE OF THE PLASMA C-REACTIVE PROTEIN/ALBUMIN RATIO FOR ACUTE KIDNEY INJURY IN ACUTE PANCREATITIS PATIENTS. Journal of Military Pharmaco-medicine, 50(si4), 269-277. https://doi.org/10.56535/jmpm.v50si4.1624

ASSESSMENT OF THE VALUE OF THE PLASMA C-REACTIVE PROTEIN/ALBUMIN RATIO FOR ACUTE KIDNEY INJURY IN ACUTE PANCREATITIS PATIENTS

Van Cong Pham1, , Quy Lam Ngo1, Quang Huy Nguyen1, Van Ba Dang1, Van Thuan Nguyen1, Dinh Dien Vu1, Huu Nhuong Le2, Thi Phuong Thao Phung3, Minh Duong Vu1
1 Bệnh viện Quân y 103, Học viện Quân y
2 Bệnh viện Quân y 354
3 Bệnh viện Công an Thành phố Hà Nội

Main Article Content

Abstract

Objectives: To assess the prognostic value of C-reactive protein/Albumin (CAR) for acute kidney injury (AKI) in acute pancreatitis (AP) patients. Methods:A cross-sectional descriptive, analytical study was conducted on 159 patients with AP at Bach Mai Hospital from October 2021 to December 2022. Plasma C-reactive protein (CRP) and Albumin were measured from venous blood samples at hospital admission, and these values were used to predict AKI during the course of treatment. Results: AP patients with AKI had a higher SOFA score (sequential organ failure assessment score) score compared to the group without AKI (7.6 ± 3 vs. 3.3 ± 1, p < 0.05), lower mean blood pressure on admission (54 ± 12mmHg vs. 76 ± 17mmHg, p < 0.05), lower Albumin (28.4 ± 5 g/L vs. 34.9 ± 5.7 g/L, p < 0.001), higher CRP (122.8 ± 20.6 mg/L vs. 27.3 ± 12.4 mg/L, p < 0.05). The CAR had a predictive value for AKI with an area under the curve (AUC) = 0.735 (p < 0.001; 95%CI: 0.605 - 0.865). CAR = 1.0205 had a sensitivity (Se) of 60.9% and specificity (Sp) of 84.5%. Conclusion: CAR is a simple, easily applicable index with prognostic value for AKI in AP patients.

Keywords

Acute pancreatitis, Acute kidney injury, CRP/Albumin ratio

Article Details

References

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