FACTORS ASSOCIATED WITH TREATMENT RESPONSE TO TRANSCRANIAL DIRECT CURRENT STIMULATION IN PATIENTS WITH SCHIZOPHRENIA
Main Article Content
Abstract
Objectives: To investigate the factors related to treatment response to transcranial direct current stimulation (tDCS) in patients with schizophrenia. Methods: A prospective, cross-sectional descriptive, longitudinal analytical study was conducted on 70 patients with schizophrenia who were treated with tDCS combined with pharmacotherapy. A treatment response was defined as a decrease of ≥ 50% on the Positive Syndrome Scale for Schizophrenia after 2 weeks of treatment. Results: After 2 weeks of treatment, the proportion of patients with a good treatment response was 61.4%. Females and those aged £ 30 years had an odds ratio for good treatment response of 3.38 (95%CI: 1.25 - 9.09) and 2.78 (95%CI: 1.01 - 7.58), respectively, compared to males and those aged > 30 years. In contrast, relapse status and the characteristics of alpha and slow waves on the electroencephalogram were not associated with treatment response to tDCS in patients with schizophrenia. Conclusion: Female gender and younger age are factors associated with a good treatment response to tDCS in patients with schizophrenia.
Keywords
Associated factor, Transcranial direct current stimulation, Schizophrenia
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References
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