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Date Published: 10/12/2025
Abstract Views: 12
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DOI: 10.56535/jmpm.v50si4.1486
Issue
Vol. 50 No. si4 (2025): JOURNAL OF MILITARY PHARMACO-MEDICINE - SPECIAL ISSUE 12/2025
Section
Special issue celebrating the 75th anniversary of Military Hospital 103
How to Cite
Nguyen, P. L., Quan, T. N., Do, L. H., Do, V. T., Nghiem, D. T., & Nguyen, B. T. (2025). THE CORRELATION BETWEEN CLINICAL AND PARACLINICAL CHARACTERISTICS AND POLYP TISSUE EOSINOPHIL INDEX IN PATIENTS WITH CHRONIC RHINOSINUSITIS WITH NASAL POLYPS. Journal of Military Pharmaco-medicine, 50(si4), 510-518. https://doi.org/10.56535/jmpm.v50si4.1486

THE CORRELATION BETWEEN CLINICAL AND PARACLINICAL CHARACTERISTICS AND POLYP TISSUE EOSINOPHIL INDEX IN PATIENTS WITH CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

Phi Long Nguyen1, Thanh Nam Quan1, , Lan Huong Do1, Van Tung Do2, Duc Thuan Nghiem3, Ba Tung Nguyen3
1 Bộ môn - Khoa Tai Mũi Họng, Bệnh viện Quân y 103, Học viện Quân y
2 Khoa Tai Mũi Họng, Bệnh viện Quân y 7, Cục Hậu cần - Kỹ thuật, Quân khu 3
3 Học viện Quân y

Main Article Content

Abstract

Objectives: To analyze the correlation between clinical, paraclinical characteristics of chronic rhinosinusitis with nasal polyps (CRSwNP) and the eosinophil index in polyp tissue. Methods: A cross-sectional descriptive study was conducted on 51 patients diagnosed with CRSwNP who were treated at the Department of Otorhinolaryngology, Military Hospital 103, from March 2024 to May 2025. Results: The group with elevated eosinophils in polyp tissue showed a predominance of the following symptoms and signs: Mucopurulent nasal discharge (40.0%), thick purulent discharge (52.0%), severe nasal obstruction (96.0%), severe olfactory dysfunction (12.0%), severe sinus pain (44.0%), thick purulent discharge (80.0%), severe mucosal edema (20.0%), and bilateral nasal polyps (96.0%), all higher than those in the non-eosinophilic group, with statistically significant differences (p < 0.05). On CT scan, the Lund-Mackay score in the eosinophilic group was 6.39 ± 1.73, higher than that in the non-eosinophilic group (4.02 ± 0.9), with a statistically significant difference (p < 0.05). Conclusion: The eosinophilic group in polyp tissue predominates in patients with mainly severe subjective symptoms, more extensive and severe lesions compared to the non-eosinophilic group.

Keywords

Increased tissue eosinophilia, Chronic rhinosinusitis, Nasal polyp

Article Details

References

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