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Date Published: 10/12/2025
Abstract Views: 10
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DOI: 10.56535/jmpm.v50si4.1481
Issue
Vol. 50 No. si4 (2025): JOURNAL OF MILITARY PHARMACO-MEDICINE - SPECIAL ISSUE 12/2025
Section
Special issue celebrating the 75th anniversary of Military Hospital 103
How to Cite
Nguyen, V. P., Tran, V. T., Le, V. N., Nguyen, M. N., Nguyen, V. T., Nguyen, H. T., Ngo, Q. L., & Ta, B. T. (2025). PROGNOSTIC VALUE OF THE LACTATE/ALBUMIN RATIO IN SEPTIC PATIENTS TREATED AT 103 MILITARY HOSPITAL. Journal of Military Pharmaco-medicine, 50(si4), 403-411. https://doi.org/10.56535/jmpm.v50si4.1481

PROGNOSTIC VALUE OF THE LACTATE/ALBUMIN RATIO IN SEPTIC PATIENTS TREATED AT 103 MILITARY HOSPITAL

Viet Phuong Nguyen1, , Viet Tien Tran2, Van Nam Le1, Minh Nam Nguyen1, Vu Trung Nguyen1, Hoang Thanh Nguyen1, Quy Lam Ngo1, Ba Thang Ta1
1 Bệnh viện Quân y 103, Học viện Quân y
2 Học viện Quân y

Main Article Content

Abstract

PROGNOSTIC VALUE OF THE LACTATE/ALBUMIN RATIO IN SEPTIC PATIENTS TREATED AT 103 MILITARY HOSPITAL

ABSTRACT

Objective: To determine the prognostic value of the lactate/albumin ratio (LAR) in patients with sepsis treated at 103 Military Hospital. Subjects and Methods: A retrospective, cross-sectional descriptive study was conducted on 81 patients aged ≥18 years, diagnosed with sepsis and treated at 103 Military Hospital from January 2023 to December 2024. Results: The mean age was 60.0 ± 14.5 years; 59.3% were male. The non-survivor group had higher lactate levels (7.5 ± 2.2 mmol/L vs. 4.0 ± 1.5 mmol/L; p < 0.01), lower albumin levels (20.0 ± 5.1 g/l vs. 24.0 ± 6.8 g/l; p > 0.05), and higher LAR values (3.75 ± 1.10 vs. 1.67 ± 0.70; p < 0.01). In predicting mortality, LAR showed the highest AUC (0.76) with a cutoff of 2.2, sensitivity 73.7%, and specificity 71.0%. Lactate had an AUC of 0.72 (cutoff 3.8 mmol/L; sensitivity 72.0%, specificity 68.0%). Albumin had the lowest AUC (0.66) with lower sensitivity and specificity. Conclusion: The lactate/albumin ratio is a superior prognostic indicator of in-hospital mortality compared to lactate or albumin alone. It may serve as a simple and effective clinical tool for early risk stratification in septic patients.

 

 

Keywords

Sepsis, Lactate/albumin ratio, Mortality prediction

Article Details

References

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