CHANGES IN LEFT ATRIAL STRAIN AND STIFFNESS USING SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH END-STAGE CHRONIC KIDNEY DISEASE
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Abstract
Objectives: To investigate the changes in left atrial strain and stiffness using speckle tracking echocardiography in patients with end-stage chronic kidney disease. Methods:Across-sectional descriptive study with a control group was conducted on 2 groups, including 62 patients diagnosed with end-stage chronic kidney disease at Military Hospital 103, from October 2024 to April 2025 and a control group consisted of 42 healthy people, similar in age and gender. Results: The left atrial size in the end-stage chronic kidney disease group was higher than that in the control group (p < 0.01). The left atrial reservoir strain (LASr) and conduit (LAScd) in both the 4-chamber and 2-chamber cross-sections were significantly reduced compared to the control group. The left atrial stiffness index (LASI) in the end-stage chronic kidney disease group was higher than that in the control group (0.23 ± 0.08 vs. 0.15 ± 0.07, p < 0.01). Conclusion: In the end-stage chronic kidney disease group, LASr was higher, and LAScd was lower than in the control group. LASI in the end-stage chronic kidney disease group was higher than that in the control group.
Keywords
Strain, Left atrial stiffness, Speckle-tracking echocardiography, End-stage chronic kidney disease
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References
2. Mark PB, Mangion K, Rankin AJ, et al. Left ventricular dysfunction with preserved ejection fraction: The most common left ventricular disorder in chronic kidney disease patients. Clin Kidney J. 2022; 15(12):2186-2199.
3. Wang W, Reyes JL, Oyenuga A, et al. Association of left atrial function with incident chronic kidney disease in older adults. Mayo Clin Proc Innov Qual Outcomes. 2024; 8(4):343-355.
4. Yildirim U, Akcay M, Coksevim M, et al. Comparison of left atrial deformation parameters between renal transplant and hemodialysis patients. Cardiovasc Ultrasound. 2022; 20(1):5.
5. Penachio FM, Diniz MFR, Laurino RSP, et al. Speckle-tracking: Incremental role in diastolic assessment of pediatric patients with chronic kidney disease. Arq Bras Cardiol. 2024; 121(3): e20230131.
6. Stevens Paul E, Ahmed Sofia B, Carrero Juan Jesus, et al. KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International. 2024; 105(4):117-314.
7. Hoit Brian D. Left atrial size and function. JACC. 2014; 63(6):493-505.
8. Đỗ Văn Chiến, Đặng Thị Vũ Diệu, Nguyễn Thị Thu Hoài. Nghiên cứu sự biến đổi thể tích và sức căng nhĩ trái bằng siêu âm tim ở bệnh nhân thận mạn. Tạp chí Y Dược Lâm sàng 108. 2023; 18(3).