CHANGES IN LEFT ATRIAL STRAIN AND STIFFNESS USING SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH END-STAGE CHRONIC KIDNEY DISEASE

Duy Toan Nguyen1,2, Thanh Nam Le1, Thi Thu Ha Nguyen1,2, Vu Thu Ha Pham1,2,
1 Học viện Quân y
2 Bệnh viện Quân y 103, Học viện Quân y

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Abstract

Objectives: To investigate the changes in left atrial strain and stiffness using speckle tracking echocardiography in patients with end-stage chronic kidney disease. Methods:Across-sectional descriptive study with a control group was conducted on 2 groups, including 62 patients diagnosed with end-stage chronic kidney disease at Military Hospital 103, from October 2024 to April 2025 and a control group consisted of 42 healthy people, similar in age and gender. Results: The left atrial size in the end-stage chronic kidney disease group was higher than that in the control group (p < 0.01). The left atrial reservoir strain (LASr) and conduit (LAScd) in both the 4-chamber and 2-chamber cross-sections were significantly reduced compared to the control group. The left atrial stiffness index (LASI) in the end-stage chronic kidney disease group was higher than that in the control group (0.23 ± 0.08 vs. 0.15 ± 0.07, p < 0.01). Conclusion: In the end-stage chronic kidney disease group, LASr was higher, and LAScd was lower than in the control group. LASI in the end-stage chronic kidney disease group was higher than that in the control group.

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References

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