ĐẶC ĐIỂM KHÁNG SINH ĐỒ MỘT SỐ LOẠI VI KHUẨN HAY GẶP Ở BỆNH VIÊM MŨI XOANG MẠN TÍNH

Abstract

Objective: To describe the antibiotic susceptibility patterns of common bacterial pathogens isolated from patients with chronic rhinosinusitis (CRS). Subjects and Methods: A prospective, descriptive case-series study was conducted on 69 patients diagnosed with CRS who had positive bacterial cultures at the 103 Military Hospital from May 2024 to March 2025. Results: Staphylococcus aureus (S. aureus) accounting for 60.9%, followed by Streptococcus pneumoniae (S. pneumoniae) at 18.8%, and Haemophilus influenzae (H. influenzae) at 7.2%. Three other bacteria—Moraxella catarrhalis (M. catarrhalis), Pseudomonas aeruginosa (P. aeruginosa), and Klebsiella pneumoniae (K. pneumoniae)—each accounted for 4.3%. S. aureus showed 100% sensitive with Dalfopristin, Linezolid, Vancomycin, and Rifamycin, but exhibited approximately 70% resistance to quinolones and clindamycin. S. pneumoniae was 100% susceptible to Cefotaxime, Levofloxacin, Moxifloxacin, Linezolid, Vancomycin, and Tigecycline, but showed completely resistance to Erythromycin, Chloramphenicol, Rifamycin, and Trimethoprim/Sulfamethoxazole, and 76.9% resistance to Clindamycin. H. influenzae was fully sensitive (100%) to Piperacillin/Tazobactam, Ciprofloxacin, Levofloxacin, and Meropenem, but demonstrated 20% resistance to Amoxicillin and second- and third-generation cephalosporins. Conclusion: The bacterial profile in CRS patients at 103 Military Hospital remains consistent with existing literature and prior studies, although it differs from that of acute rhinosinusitis. Most isolates were susceptible to first-line beta-lactams and cephalosporins; however, high resistance rates were observed for the quinolone group.