Article Sidebar

PDF
Date Published: 28/08/2025
Abstract Views: 25
Views PDF: 12
DOI: https://doi.org/10.56535/jmpm.v50i6.1330
Issue
Vol. 50 No. 6 (2025): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 6 - 2025
Section
Articles
How to Cite
Đinh, T. T. T., Nguyễn, T. H., Lương, H. T., & Lê, V. Đ. (2025). EVALUATION OF RESULTS OF LABOR INDUCTION BY PROPESS IN PREGNANT WOMEN WITH PREMATURE RUPTURE OF MEMBRANES AT HA NOI OBSTETRIC AND GYNECOLOGY HOSPITAL IN 2024. Journal of Military Pharmaco-medicine, 50(6), 194-203. https://doi.org/10.56535/jmpm.v50i6.1330

EVALUATION OF RESULTS OF LABOR INDUCTION BY PROPESS IN PREGNANT WOMEN WITH PREMATURE RUPTURE OF MEMBRANES AT HA NOI OBSTETRIC AND GYNECOLOGY HOSPITAL IN 2024

Đinh Thị Thu Trang1,2, Thu Hà Nguyễn1, , Lương Hoàng Thành1,2, Văn Đạt Lê1,2
1 Trường Đại học Y Dược - Đại học Quốc gia Hà Nội
2 Bệnh viện Phụ sản Hà Nội

Main Article Content

Abstract

Abstract


Objectives: To evaluate the outcomes of labor induction using Propess in pregnant women with premature rupture of membranes (PROM). Methods: A retrospective,


cross-sectional descriptive study was conducted on 56 pregnant women with PROM at Hanoi Obstetrics and Gynecology Hospital in 2024, eligible for vaginal delivery and underwent labor induction by Propess. Outcomes before and after labor induction were assessed through changes in the Bishop score, rates of vaginal delivery, cesarean delivery, and associated complications. Results: The Bishop score increased by an average of 4.09 points after Propess administration compared to baseline. The success rate of cervical ripening (defined as cervical dilation > 3cm) was 62.5%. Successful labor induction leading to vaginal delivery was achieved in 51.79% of the study population. Pregnant women who delivered vaginally within 12 hours of Propess insertion accounted for 68.96%. Among the 27/56 cesarean deliveries, the most common indication for surgery was failure of cervical progression, accounting for 66.67% of cases. Most pregnant women who underwent labor induction by Propess experienced no serious adverse events or complications. Conclusion: Propess is effective in cervical ripening and labor induction in cases of premature rupture of membranes. Due to the potential adverse effects, the use of Propess for labor induction must follow strict protocols and be closely monitored.

Article Details

Keywords

Bishop score, Labor induction, Premature rupture of membranes, Propress

References

1. BM Mercer. Preterm premature rupture of the membranes: Current approaches to evaluation and management. Obstet Gynecol Clin North Am. 9/2005; 32(3):411-428. DOI: 10.1016/j.ogc. 2005.03.003.
2. Thái Bằng. Nghiên cứu hiệu quả khởi phát chuyển dạ bằng Propess tại Bệnh viện Đa khoa Quốc tế Vinmec Nha Trang. Tạp chí Phụ sản. 2023; 21(4-5):75-81.
3. Dương Mỹ Linh. Kết quả khởi phát chuyển dạ bằng Dinoprostone trên thai phụ có chỉ định chấm dứt thai kỳ. Tạp chí Y học Việt Nam. 8/2023; 529(1).
4. Vũ Văn Vinh. Nghiên cứu hiệu quả khởi phát chuyển dạ của Prostaglandin E2 trên những thai phụ thiểu ối tại Bệnh viện Phụ sản Hà Nội. Luận văn Thạc sĩ Y khoa, Đại học Y Hà Nội. 2012.
5. Phạm Chí Kông. Nghiên cứu hiệu quả khởi phát chuyển dạ bằng propess đặt âm đạo. TC Phụ sản. 2021;19(1):38-47
6. Cynthia Abraham, N Meirowitz, N Kohn. Labor induction for premature rupture of membranes using vaginal misoprostol versus dinoprostone vaginal insert. Am J Perinatol. 3/2014; 31(3):181-186.
7. Flavie Sire, L Ponthier, JL Eyraud, C Catalan, Y Aubard, P Coste Mazeau. Comparative study of dinoprostone and misoprostol for induction of labor in patients with premature rupture of membranes after 35 weeks. Sci Rep. 9/2022; 12(1):14996.
8. Ngô Thị Thùy Dương. Nghiên cứu hiệu quả gây chuyển dạ của Dinoprostone trên thai phụ đủ tháng tại khoa đẻ Bệnh viện Phụ sản Trung ương. Luận văn Thạc sĩ Y khoa, Trường Đại học Y Hà Nội. 2020.
9. Wing DA, Rahall A, Jones MM, Goodwin TM, Paul RH. Misoprostol: An effective agent for cervical ripening and labor induction. Am J Obstet Gynecol. 2001; 184(2):139-146. DOI:10.1067/ mob.2001.109417.