FACTORS RELATED TO ARRHYTHMIA IN BREAST CANCER PATIENTS RECEIVING CHEMOTHERAPY WITH AN ANTHRACYCLINE REGIMEN

Dinh Viet Nguyen1, , Van Dong Tran2, Hoc Huan Vu3, Thi Hien Nguyen1, Duc Thuan Nguyen4
1 Bệnh viện Đa khoa tỉnh Phú Thọ
2 Bệnh viện Bạch Mai
3 Bệnh viện Đa khoa Quốc tế Hải Phòng
4 Học viện Quân y

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Abstract

Objectives: To investigate several factors associated with arrhythmia in breast cancer patients receiving anthracycline-based chemotherapy regimens. Methods: A respective, cross-sectional descriptive study was conducted on 52 breast cancer patients treated at Phu Tho Provincial General Hospital from August 2021 to September 2022. Clinical characteristics, treatment regimens, cancer stages, and manifestations of arrhythmias were collected and statistically analyzed. Results:Patients < 50 years of age had a significantly higher rate of arrhythmia compared to those aged ≥ 50 (p < 0.05). Sinus tachycardia was the most common type of arrhythmia, more prevalent in patients < 50 years, those receiving high-dose ACT regimens, and those at advanced cancer stages (III, IV) compared to other groups (p < 0.05). Conclusion: Arrhythmia in breast cancer patients treated with anthracycline is associated with age, chemotherapy regimen, and cancer stage. Cardiac monitoring should be emphasized in high-risk groups to minimize complications and improve overall treatment effectiveness.

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References

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