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Date Published: 28/08/2025
Abstract Views: 39
Views PDF: 16
DOI: https://doi.org/10.56535/jmpm.v50i6.1320
Issue
Vol. 50 No. 6 (2025): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 6 - 2025
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Articles
How to Cite
Tran, B. H., Bui, T. T. H., Phạm, T. H., Do, T. H. L., Dang, V. D., Nguyen, V. T., & Vu, T. A. (2025). RESEARCH ON PREPARATION OF ECHINACOSIDE-RICH LIQUID EXTRACT FROM CISTANCHE DESERTICOLA. Journal of Military Pharmaco-medicine, 50(6), 29-38. https://doi.org/10.56535/jmpm.v50i6.1320

RESEARCH ON PREPARATION OF ECHINACOSIDE-RICH LIQUID EXTRACT FROM CISTANCHE DESERTICOLA

Tran Ba Hieu1, , Bui Thi Thu Ha2, Thái Hà Phạm3, Do Thi Huong Lan2, Dang Van Diep2, Nguyen Van Thinh1, Vu Tuan Anh1
1 Viện Nghiên cứu Y Dược học Quân sự, Học viện Quân y
2 Viện Đào tạo Dược, Học viện Quân y
3 Học viện Y Dược học Cổ truyền Việt Nam

Main Article Content

Abstract

Abstract


Objectives: to prepare echinacoside-rich liquid extract from Cistanche deserticola. Methods: using echinacoside level and extraction efficiency to determine the methods as well as parameters for the liquid extraction process of echinacoside-rich Cistanche deserticola at a scale of 1 kg/batch. Results: the ultrasonic heating extraction method was selected, and the parameters were optimized, including the extraction solvent, which was ethanol (40%), the solvent/medicinal material ratio, which was 20/1, the extraction temperature, which was 60°C, and 2 extractions with an extraction time each time of 60 minutes. Conclusion: an extraction process of echinacoside-rich liquid extracted from Cistanche deserticola at 1 kg/batch scales was successfully established.


Keyword: Cistanche, echinacoside, extraction

Article Details

Keywords

cistanche, echinacoside, extraction

References

1. Fu Z, Fan X, Wang X, et al. Cistanches Herba: An overview of its chemistry, pharmacology, and pharmacokinetics property. Journal of Ethnopharmacology. 2018; 219:233-247.
2. J Liu, L Yang, Y Dong, B Zhang, X Ma. ECHe, an inestimable natural product in treatment of neurological and other disorders. Molecules. 2018; 23(5):1213.
3. Bộ Y tế. Dược điển Việt Nam V. 2017.
4. Beitao Dong, Xiaofan Yuan, et al. Ultrasound-assisted aqueous two-phase extraction of phenylethanoid glycosides from Cistanche deserticola Y. C. Ma stems. Journal of Separation Science. 2015; 38(7):1194-1203.
5. Wenjing Pei, Ruili Guo, Jinli Zhang, Xueqin Li. Extraction of phenylethanoid glycosides from cistanche tubulosa by high-speed shearing homogenization extraction. Journal of AOAC International. 18-0039.
6. Chieh-Ju Wu, Mei-Yin Chien, Nan-Hei Lin, et al. Echinacoside isolated from cistanche tubulosa putatively stimulates growth hormone secretion via activation of the ghrelin receptor. Molecules. 2019; 24(4):720.