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COMPARISON OF THE EFFECTS OF LIDOCAINE AND PROPOFOL ON HEMODYNAMIC RESPONSE AND AIRWAY REFLEX DURING THE TRACHEAL EXTUBATION PHASE FOLLOWING COSMETIC SURGERY
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Abstract
Abstract
Objectives: To compare the effectiveness of lidocaine and propofol in controlling hemodynamic response and airway reflex during the tracheal extubation phase following cosmetic surgery. Methods: A prospective, clinical interventional, randomized grouping, comparative study was conducted on 60 patients undergoing cosmetic surgery with ASA I-II (according to American Society of Anesthesiologists). Patients were randomly divided into two groups: Group L (30 patients) received 1.5 mg/kg of intravenous lidocaine, and group P (30 patients) received 0.5 mg/kg of intravenous propofol when the patient began to breathe spontaneously, and extubation was performed after 5 minutes. The two groups were compared in terms of hemodynamic changes and airway reflex (cough, abnormal movements, and bronchospasm) before and after extubation. Results: Group P had more hemodynamic stability than group L, which was shown at the time immediately after extubation (T3): Heart rate and mean arterial pressure in group P were statistically significantly lower than in group L (p < 0.05). Group L showed superior suppression of coughing and airway reflex, with lower cough scores and incidence of laryngospasm (p < 0.001). Conclusion: Propofol is preferred for hemodynamic control, while lidocaine is more effective in airway reflex. Drug choice should be tailored to clinical goals and patient characteristics.
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Keywords
Lidocaine, Propofol, Cosmetic surgery, Tracheal extubation
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