SỰ TÁC ĐỘNG LÊN THAY ĐỔI ĐIỆN NÃO ĐỒ TRONG GÂY MÊ CỦA MỘT SỐ THUỐC MÊ THƯỜNG DÙNG

Abstract

Using electroencephalogram (EEG) monitors to assess the depth of anesthesia has become increasingly prevalent due to their accuracy and reliability in detecting intraoperative neurophysiological brain states. These devices typically provide outputs such as EEG-derived indices, EEG spectrograms, and raw EEG data. While EEG-derived indices offer a simplified and rapid means to determine the depth of anesthesia, it is often assumed that the same index value reflects an equivalent level of unconsciousness across different anesthetic agents. However, anesthetics target distinct molecular mechanisms and neural circuits, resulting in unique brain states. To fully appreciate the validity and reliability of depth of anesthesia assessments, it is essential to understand how EEG characteristics change depending on the anesthetic used. This review aims to explore the specific molecular and neural circuit targets, as well as the characteristic raw EEG patterns spectrogram signatures, and behavioral alterations induced by common anesthetic agents.