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CLINICAL CHARACTERISTICS OF PATIENTS UNDERGOING LONG-TERM GLUCOCORTICOID THERAPY AT THE OUTPATIENT CLINIC OF NGUYỄN TRI PHƯƠNG HOSPITAL
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Abstract
Objectives: This study aims to characterize the clinical manifestations of patients undergoing long-term glucocorticoid therapy at the outpatient clinic of Nguyễn Tri Phương Hospital and to ascertain the prevalence of glucocorticoid-induced secondary adrenal insufficiency through the insulin tolerance test. Methods: A cross-sectional study was conducted on 96 patients undergoing long-term glucocorticoid therapy at the outpatient clinic of Nguyễn Tri Phương Hospital between May 2023 and February 2024. Results: Among 96 patients, the most commonly observed clinical manifestations included abdominal obesity (24%), thin and easily bruised skin (15,6%), fatigue (13,5%), exhaustion (11,5%), loss of appetite (11,5%), moon face (9,4%), cataracts (8,3%), dizziness (4,2%), abdominal or thigh striae (4,2%), nausea and vomiting (5,2%), buffalo hump (3,1%), and neuropsychiatric symptoms (3,1%). The prevalence of glucocorticoid-induced secondary adrenal insufficiency, as determined by the insulin tolerance test, was 58,3%. Conclusion: Patients receiving long-term glucocorticoid therapy exhibit a wide range of clinical symptoms. The insulin tolerance test confirmed a 58,3% prevalence of secondary adrenal insufficiency, underscoring the importance of early detection and appropriate management in this patient population.
Keywords: Clinical characteristics, long-term glucocorticoid therapy, insulin tolerance test.
Article Details
Keywords
Clinical characteristics, long-term glucocorticoid therapy, insulin tolerance test.
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