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ANALYSIS OF MOTOR SYMPTOMS IN EARLY ONSET PARKINSON'S DISEASE
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Abstract
Objective: Analyze the characteristics of motor symptoms of early-onset Parkinson's disease (EOPD). Method: Prospective, cross-sectional study with analysis on 135 patients with early-onset Parkinson's disease from April 2019 to December 2021. Patients information was collected according to a unified medical record form. Disease severity and type were assessed according to the MDS-UPDRS (Unified Parkinson's Disease Rating Scale), disease stage according to Hoehn and Yahr. Results: At the time of disease onset, tremor symptoms appeared at the highest rate (72.6%). At the time of the study, hypokinesia and rigidity symptoms accounted for a higher proportion, 97.8% and 93.3%, respectively. Dystonia accounted for the smallest proportion at both times, 3% and 17%, respectively. The disease type "Predominantly rigid/hypokinesia" had the highest rate of 65.2%. The proportion of patients with mild disease was the highest (58.5%), with an average MDS-UPDRS score of 33.38 (±17.62). Patients in the early stage of the disease accounted for the majority (63.7%). Conclusion: At the time of the study, hypokinesia was the most common symptom. Dystonia was the least common symptom. The “Predominantly rigid/hypokinesia” form had the highest prevalence. Patients in the early
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Keywords
Parkinson's disease, Early onset, Motor symptoms
References
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