MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN TỔN THƯƠNG THẬN CẤP Ở NGƯỜI BỆNH NHỒI MÁU NÃO CẤP ĐƯỢC LẤY HUYẾT KHỐI BẰNG DỤNG CỤ CƠ HỌC
Main Article Content
Abstract
Objectives: To determine the incidence of acute kidney injury (AKI), identify factors associated with AKI, and evaluate outcomes in patients with acute ischemic stroke undergoing mechanical thrombectomy. Methods: A descriptive observational study. Results: Study conducted on 272 patients with acute ischemic stroke undergoing mechanical thrombectomy revealed an incidence of AKI was 12.5%. The median age was 69 years in the AKI group and 68 years in the non-AKI group. The proportion of males in the AKI group was 79.4%, compared to 51.3% in the non-AKI group. The AKI group had a higher prevalence of diabetes mellitus (35.3%) than the non-AKI group (11.3%), with a significant difference (p<0.05). Factors associated with AKI included complications such as cerebral edema, hospital-acquired pneumonia, mechanical ventilation, and the use of medications (mannitol, diuretics, nephrotoxic antibiotics, and NSAIDs). Patients with AKI had higher NIHSS scores at discharge (13 vs. 10), a higher proportion of poor functional outcomes (mRS 3–6: 73,5% vs. 54.2%), longer hospital stays (18.9 ± 11.5 days vs. 13.1 ± 8.4 days) compared to the non-AKI group. Conclusion: Acute kidney injury is a complication occuring in 12.5% of patients with acute ischemic stroke undergoing mechanical thrombectomy and is associated with worse outcomes in this population. The study revealed the necessity of closely monitoring renal function and promptly managing risk factors that may increase the likelihood of AKI.
Article Details
Keywords
Acute kidney injury, acute ischemic stroke, mechanical thrombectomy
References
2. Y Huang, C Wan và G Wu . Acute kidney injury after a stroke: A PRISMA-compliant meta-analysis. Brain Behav. 2020; 10(9):01722.
3. M Oliveira, et al. Early acute kidney injury in stroke patients submitted to endovascular treatment: A cohort study. J Clin Med. 2024; 13(22).
4. S Fandler-Höfler, et al. Acute and chronic kidney dysfunction and outcome after stroke thrombectomy. Transl Stroke Res. 2021; 12(5):791-798.
5. P Wrona, et al. Risk factors of acute kidney injury during hospitalization in acute ischaemic stroke patients undergoing mechanical thrombectomy. Postepy Kardiol Interwencyjnej. 2024; 20(1):89-94.
6. SY Lin, et al. Incidence and risk factors for acute kidney injury following mannitol infusion in patients with acute stroke: A retrospective cohort study. Medicine (Baltimore). 2015; 94(47):2032.
7. Hong‐Jie Jhou, et al. Contrast‐associated acute kidney injury after endovascular therapy for acute ischemic stroke: A meta‐analysis. Stroke: Vascular and Interventional Neurology. 2022; 2(6):000296.
8. G Tsagalis, et al. Long-term prognosis of acute kidney injury after first acute stroke. Clin J Am Soc Nephrol. 2009; 4(3):616-622.
9. Julia Arnold, et al. Incidence and impact on outcomes of acute kidney injury after a stroke: A systematic review and meta-analysis. BMC Nephrology. 2018; 19(1):283.