THE VALUE OF PLASMA AMMONIA TO PLATELET INDEX FOR PREDICTION OF ESOPHAGEAL VARICES IN CIRRHOTIC PATIENTS
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Abstract
Objective: To evaluate the value of Ammonia to Platelet index (API) for prediction of esophageal varices (EV) in patients with cirrhosis. Subject and method: cross-sectional descriptive study carried out on 103 cirrhotic patients in Digestive Department of 103 military hospital. Determine platelet count and venous ammonia concentration by kinetic enzymatic method with glutamate dehydrogenase. Results: API had the very good value for detection of EV with AUROC 0.929, at the cut-off value of 0.48 with 80.6% sensitivity and 100% specificity. API predicted large EV with AUROC of 0.876, at the cut-off value of 0.48 with 88.3% sensitivity and 73.1% specificity. Conclusion: API was the useful non-invasive index in prediction of the presence of EV in cirrhotic patients.
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Keywords
Ammonia, esophageal varices
References
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