ĐẶC ĐIỂM PHÂN BỐ VÀ TÍNH KHÁNG KHÁNG SINH CỦA BURKHOLDERIA CEPACIA PHÂN LẬP ĐƯỢC TỪ BỆNH NHÂN TẠI BỆNH VIỆN QUÂN Y 103

Abstract

Objective: Study distribution and antibiotic resistance characteristics of Burkholderia cepacia species isolated from Military Hospital 103 in the period from 2014 to 2022.

Subject and methods: This was a crosssectional study. The subject of the study was B. cepacia isolated from Military Hospital 103 in the period from 2014 to 2022.

Result: 101 stains of pathogenic bacteria Burkholderia cepacia have been isolated during reseach process. Age: from 50 to 69 (40.6%), ≥ 70 (29,7%); Male/ female ratio: 2.9/1. The specific distribution ratio is as follows: internal medicine departments account for 55.4%, ICU accounts for 25.7%. Blood specimens account for 79.2%, respiratory specimens account for 18.8%. B. cepacia has an antibiotic resisitance rate of over 90% for the following antibiotics: amoxicillin, extended spectrum penicillins (piperacillin, ticarcillin), imipenem, aminoglycoside (gentamycin, tobramycin), fosmicin; low resistance rate for levofloxacin 24.3%, ceftazidime 15.7%, meropenem 12.8% and lowest for trimethoprim/sulfamethoxazole 7.0%.

Conclusion: Burkholderia cepacia commonly causes disease in patients over 50 years old, male gender, mostly isolated on blood and respiratory specimens. B. cepacia has high resistance rates to extended spectrum penicillins antibiotics, aminoglycoside antibiotics, and low resistance rates to levofloxacin, ceftazidime, meropenem and trimethoprim/sulfamethoxazole.