ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA BỆNH NHÂN UNG THƯ BIỂU MÔ TUYẾN VÚ GIAI ĐOẠN III ĐƯỢC ĐIỀU TRỊ HÓA CHẤT TÂN BỔ TRỢ VÀ PHẪU THUẬT TẠI BỆNH VIỆN K

Abstract

Objective: To evaluate the clinical and paraclinical characteristics of stage III breast cancer patients treated with neoadjuvant chemotherapy combined with surgery.

Subjects and Methods: This cross-sectional descriptive study with longitudinal follow-up included 250 stage III breast cancer patients treated with neoadjuvant chemotherapy and surgery at the Breast Surgery Department, K Hospital (Tan Trieu campus), from August 2021 to October 2022.

Results: The average age of the patients was 50.14 ± 11.60 years. The majority of patients self-detected the tumor (87.60%), with the most common location being the upper outer quadrant (54.00%) and an average tumor size of 51.80 ± 25.84 mm. The tumors were typically hard (91.09%) and poorly mobile (62.75%). Axillary lymph nodes were involved in 92.8% of patients. Ultrasound findings revealed that 85.20% of patients had a single tumor, with a size primarily between 2-5 cm, and 56.40% were classified as BIRADS 5. Histopathological analysis showed that 82.40% of the cases were invasive carcinoma of no special type, with 44.80% being histological grade II.

Conclusion: Stage III breast cancer patients at K Hospital often self-detect the disease through the presence of a hard and poorly mobile mass, typically located in the upper outer quadrant of the breast. Ultrasound and histopathological findings are crucial for assessing and guiding effective treatment for these patients.