ASSESSMENT OF CHANGES IN PRURITUS CONDITION ACCORDING TO THE 5-D ITCH SCALE IN HEMODIALYSIS PATIENTS OVER 3 MONTHS AT MILITARY HOSPITAL 103
Main Article Content
Abstract
Objectives: To investigate the progression of pruritus condition according to the 5-D itchscale in hemodialysis (HD) patients and its association with clinical and paraclinical characteristics. Methods: A cross-sectional descriptive study was conducted on 108 HD patients at Military Hospital 103 from August 2024 to August 2025. Results: The total pruritus score according to the 5-D itch scale (5-D score) increased from 10.29 to 14.43 points (accounted for 45.4%), in which the D4 score increased (1.73 to 2.80 points) and the D1 score remained unchanged (at 0- 6 hours) with statistical significance (p< 0.05). The 5-D score was associated with the duration of dialysis (p < 0.05). Age was negatively correlated with the D3 score and D4 score (with r being -0.274 and -0.245, respectively; p < 0.05). Parathyroid hormone (PTH) blood concentration was positively correlated with the 5-D score (r = 0.548, p < 0.05). The degree of anemia was associated with the 5-D score; 50% of patients with severe anemia had an increased 5-D score. Conclusion: The 5-D score in HD patients increased from 10.29 to 14.43, in which D1 and D2 scores did not increase, but the D4 score increased from little influence (1.63) to frequent influence (3.10). The longer the dialysis time, the more severe the anemia, the higher the PTH concentration, the higher the 5-D score. D1, D2, and D4 scores were inversely correlated with plasma PTH concentration.
Keywords
Change, Pruritus, 5-D itch scale, Hemodialysis
Article Details
References
2. Elman S, Hynan LS, Gabriel V, et al. The 5-D itch scale: A new measure of pruritus. Br J Dermatol. 2010; 162(3):587-593.
3. Miêu Thị Vân, Hà Phan Hải An. Tình trạng ngứa ở bệnh nhân lọc thận nhân tạo chu kỳ. Tạp chí Y học Việt Nam. 2022; 519:125-131.
4. Elman S, Hynan LS, Gabriel V, et al. The 5-D itch scale: A new measure of pruritus. Br J Dermatol. 2010; 162(3):587-593.
5. Drozdz M, Frazão J, Silva F, et al. Improvements in six aspects of quality of care of incident hemodialysis patients - a real-world experience. BMC Nephrol. 2021; 22(1):333.
6. Bộ Y tế. Việt Nam có khoảng 3,5 triệu người sống chung với đái tháo đường. Cổng thông tin điện tử Bộ Y tế. 2019. https://moh.gov.vn/chuong-trinh-muc-tieu-quoc-gia/-/asset_publisher/ 7ng11fEWgASC/content/viet-nam-co-khoang-3-5-trieu-nguoi-song-chung-voi-ai-thao-duong.
7. Pisoni RL, Wikström B, Elder SJ, et al. Pruritus in haemodialysis patients: International results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant. 2018; 21(12):3495-3505.
8. Hector Alvarado Verduzo, Shayan Shirazian. CKD-Associated Pruritus: New insights into diagnosis, pathogenesis, and management. Pubmed. 2020 May 8; 5(9):1387-1402.
9. Vandana S Mathur, Jill Lindberg. A longitudinal study of uremic pruritus in hemodialysis patients. Clin J Am Soc Nephrol. 2010; 5(8):1410-1419.
10. Narita I, Alchi B, Omori K, et al. Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients. Kidney Int. 2006; 69(9):1626-1632.