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Ngày xuất bản: 28/04/2025
Số lượt xem tóm tắt: 160
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DOI: 10.56535/jmpm.v50i4.1229
Số xuất bản
Tập 50 Số 4 (2025): TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ SỐ 4 - 2025
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Trích dẫn bài báo
Ngo, M. D., Chu, A. T., & Do, X. H. (2025). RESEARCH ON CHANGES IN SOME CHARACTERISTICS OF ACTIVATED UMBILICAL CORD BLOOD PLATELET-RICH PLASMA AFTER STORAGE AT NORMAL COLD TEMPERATURE. Tạp chí Y Dược học Quân sự, 50(4), 41-50. https://doi.org/10.56535/jmpm.v50i4.1229

RESEARCH ON CHANGES IN SOME CHARACTERISTICS OF ACTIVATED UMBILICAL CORD BLOOD PLATELET-RICH PLASMA AFTER STORAGE AT NORMAL COLD TEMPERATURE

Ngo Minh Duc1,2, , Chu Anh Tuan2, Do Xuan Hai1
1 Vietnam Military Medical University
2 Le Huu Trac National Burn Hospital

Nội dung chính của bài viết

Tóm tắt

Objectives: To evaluate sensory changes, infection, epidermal growth factor (EGF), and vascular endothelial growth factor (VEGF) concentrations in activated umbilical cord blood platelet-rich plasma (PRP) after cold storage at 2 - 6 degrees Celsius (°C). Methods: The study was conducted on 8 umbilical cord blood samples and 8 venous blood samples of adults. Results: EGF concentrations in PRP from umbilical cord blood and adult blood after activation were 115.72 (51.59 - 217.61) pg/mL and 113.04 (69.71 - 155.73) pg/mL (p > 0.05), with VEGF concentration being 193.99 (75.58 - 320.25) pg/mL and 16.12 (11.70 - 49.03) pg/mL, respectively, p < 0.01. After cold storage at 2 - 6°C for 7 days, 10 days, and 14 days, the concentrations of EGF and VEGF in PRP from activated umbilical cord blood showed no difference compared to immediately after activation (p > 0.05). PRP remained clear and yellow, with no signs of infection. Conclusion: PRP from umbilical cord blood has high VEGF concentration, no significant change in appearance, EGF and VEGF concentrations, and sterility after cold storage for 7 - 14 days.

Từ khóa

Platelet-rich plasma, Umbilical cord blood, Change, Cold storage

Chi tiết bài viết

Tài liệu tham khảo

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