PHASE ANGLE PREDICTOR OF SARCOPENIA IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE

Tóm tắt

Objectives: To examine how phase angle (PhA) contributes to sarcopenia and factors influencing sarcopenia in patients with stable ischemic heart disease (SIHD). Methods: A cross-sectional descriptive study was conducted on 52 SIHD patients who were recruited, and relevant data was gathered. Patients were diagnosed with sarcopenia based on the Asian Sarcopenia Working Group 2019 (AWGS 2019) diagnostic criteria. Differences between groups were compared, and statistically significant factors were included in the logistic regression analysis to screen for independent factors affecting sarcopenia. The receiver operating characteristics (ROC) and the area under the curve (AUC) were used to evaluate the predictive value of PhA in sarcopenia. Results: The prevalence of sarcopenia was 36.5% in patients with SIHD. Multivariate logistic regression analysis showed that PhA was an independent factor influencing sarcopenia (OR: 0.078; 95%CI: 0.012 - 0.528; p = 0.009). The AUC of PhA predicting sarcopenia was 0.852, p < 0.001; the best PhA cut-off value for sarcopenia was 5.95° for both sexes (sensitivity and specificity were 0.677 and 0.947, respectively); the PhA cut-off points were 6.05° and 5.25° for men and women, respectively (p < 0.05). Conclusion: PhA is an important determinant of sarcopenia in patients with SIHD. PhA may have an optimistic predictive value for determining sarcopenia in this population.